Expression of Virus Specific Morphological Cell Transformation Induced in E nucleated Cells
Open Access
- 1 December 1976
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung C
- Vol. 31 (11-12), 766-768b
- https://doi.org/10.1515/znc-1976-11-1232
Abstract
Chick embryo fibroblasts infected by a temperature sensitive mutant of Rous sarcoma virus were enucleated with cytochalasin B. The cytoplasts were still able to transform morphologically when shifted from nonpermissive to permissive temperature, and to revert to normal morphology when shifted from permissive to nonpermissive temperature. Apparently, the viral gene product responsible for transformation acts primarily on cytoplasmic or membrane components and not on the nucleus.Keywords
This publication has 1 reference indexed in Scilit:
- Temperature-sensitive changes in surface modulating assemblies of fibroblasts transformed by mutants of Rous sarcoma virus.Proceedings of the National Academy of Sciences, 1976