Unsaturated free fatty acids inactivate animal enveloped viruses
- 1 December 1980
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 66 (4), 301-307
- https://doi.org/10.1007/bf01320626
Abstract
Unsaturated free fatty acids such as oleic, arachidonic or linoleic at concentrations of 5–25 µg/ml inactivate enveloped viruses such as herpes, influenza, Sendai, Sindbis within minutes of contact. At these concentrations the fatty acids are inocuous to animal host cellsin vitro. Naked viruses, such as polio, SV40 or EMC are not affected by these acids. Saturated stearic acid does not inactivate any viruses at concentrations tested. Though the mode of action of unsaturated fatty acids is not understood, electronmicrographs of enveloped viruses treated by them indicate that the inactivation is associated with disintegration of the virus envelope.This publication has 20 references indexed in Scilit:
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