X-ray and Electron Diffraction of Ocular and Bone Marrow Crystals in Paraproteinemia

Abstract

Crystals in the cornea, conjunctiva, and bone marrow of a patient with a monoclonal gammopathy were analyzed by x-ray and selective-area electron diffraction. X-ray diffraction rings obtained from the abnormal crystalline deposits closely matched cholesteryl stearate patterns, and electron diffraction findings were suggestive of this lipid.