Antibodies immobilized on inorganic supports

Abstract

Antibodies and antigens can be covalently coupled to a variety of carriers, both organic and inorganic. The methods for coupling these proteins may be found scattered throughout the technical literature. This report, although it concentrates on inorganic supports, describes several of the more successful methods used in laboratories today. Each of these methods is described in enough detail for the reader to carry out the coupling method of interest in his or her own laboratory. The coupling methods have been divided into two groups, direct and silane. Under each of these general headings are described the specific methodologies.