INSULIN-, GASTRIN-, PANCREATIC POLYPEPTIDE-LIKE IMMUNOREACTIVE NEURONS IN THE BRAIN OF THE SILKWORM, BOMBYX MORI

Abstract
In adult and larval silkworm, B. mori occurrence and the distribution of neurons containing gastroenteropancreatic hormone-related peptides were studied by immunohistochemistry. Insulin-like immunoreactivity was found in 8 large neurons in the brain, and insulin-positive nerve fibers originating from them were demonstrated to reach the corpus cardiacum and corpus allatum. Gastrin-like immunoreactivity occurred in 10 or more neurons in the brain and in 2 large neurons in the prothoracic ganglion. Pancreatic polypeptide-like immunoreactivity was found in 6 small neurons in the brain.