Pyloric Function and Gall-Stone Dyspepsia

Abstract

Pyloric function was studied by means of a modified pyloric regurgitation test in which regurgitation was assessed both radiologically and biochemically. Forty-two tests were performed in 40 patients from six clinical grups: those with gall-stones with and without dyspepsia; those after cholecystectomy with and without persistent dyspepsia; and those with normal radiographs with and without dyspepsia. A close correlation was found between a history of flatulent dyspepsia and the detection of pyloric regurgitation in each matched pair of grups and in the series as a whole (P < 0·001). The time at which regurgitation occurred appeared to be significant. Regurgitation was not observed in symptomless subjects.