Ultrastructural study of spontaneous bone marrow rosette-forming cells.
Open Access
- 1 March 1977
- journal article
- research article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 72 (3), 773-777
- https://doi.org/10.1083/jcb.72.3.773
Abstract
Mouse bone marrow contains spontaneous rosette-forming cells (RFC) which include more than 70% T[thymus-derived]-cell precursors, as assessed by their transformation into .theta.-positive cells after incubation with thymic hormone. Such spontaneous RFC, examined in C57Bl/6 mouse bone marrow by EM and scanning electron microscopy, were shown to be small, inactive mouse lymphocytes when macrophages were eliminated by cell preincubation. Thymic hormone target cells apparently include small quiescent lymphocytes.Keywords
This publication has 4 references indexed in Scilit:
- Binding of autologous erythrocytes to immature T-cells.Proceedings of the National Academy of Sciences, 1975
- ISOLATION, BIOCHEMICAL CHARACTERISTICS, AND BIOLOGICAL ACTIVITY OF A CIRCULATING THYMIC HORMONE IN THE MOUSE AND IN THE HUMANAnnals of the New York Academy of Sciences, 1975
- Rosette-forming cells in the unimmunized mouse: Morphological studies with phase contrast and electron microscopyCellular Immunology, 1971
- The ultrastructure of lymphocytes.1969