Mutagenic Effects of Hydroxylamine in vivo
- 22 April 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 148 (3669), 507-508
- https://doi.org/10.1126/science.148.3669.507
Abstract
Hydroxylamine can induce any one of the four types of transition mutations in bacteriophage S13 if the mutagen is added directly to agar plates seeded with phage and bacterial indicators. The phage can also be mutated by treating the host cell with hydroxylamine before infecting it with phage. These effects of hydroxylamine in vivo contrast with the mutagenic effect in vitro, which seems to be exclusively on cytosine.Keywords
This publication has 9 references indexed in Scilit:
- Identification of the altered bases in mutated single-stranded DNAJournal of Molecular Biology, 1964
- Identification of the altered bases in mutated single-stranded DNAJournal of Molecular Biology, 1964
- Equilibrium Constants for the Synthesis of Hydroxamic Acids*Biochemistry, 1963
- Die Reaktion von Nucleinsäuren mit Hydroxylamin als Hilfsmittel für ihre definierte PartialhydrolyseHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1963
- REVERSAL OF MUTANT PHENOTYPES BY 5-FLUOROURACID: AN APPROACH TO NUCLEOTIDE SEQUENCES IN MESSENGER-RNAProceedings of the National Academy of Sciences, 1962
- The reaction of hydroxylamine with cytosine and related compoundsJournal of Molecular Biology, 1961
- The reaction of tobacco mosaic virus ribonucleic acid with hydroxylamineJournal of Molecular Biology, 1961
- THE CHEMICAL AND MUTAGENIC SPECIFICITY OF HYDROXYLAMINEProceedings of the National Academy of Sciences, 1961
- Hydroxylamine as a mutagenic and inactivating agentJournal of Molecular Biology, 1961