Sensitivity of Pertussis-Inoculated Mice to Serotonin.
- 1 June 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 95 (2), 200-201
- https://doi.org/10.3181/00379727-95-23166
Abstract
Pertussis vaccine sensitizes mice to the lethal effects of serotonin (5-hydroxytryptamine). The LD50 of serotonin in pertussis-inoculated NLA mice was 12.6 mg/kg as compared with 602 mg/kg in uninoculated NLA controls. The LD50 of serotonin in pertussis-inoculated TF mice was 7.9 mg/kg as compared with 364 mg/kg in uninoculated TF animals.Keywords
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