In the course of the study which I am making of certain cases of sprue in the laboratory of the Institute of Tropical Medicine and Hygiene, my attention has been called to the presence, in the four cases in which I have made cultures from theinflamedtongue, of a Monilia not described by Castellani and Chalmers,1or mentioned by Bahr.2My failure to find the organism in apparently normal tongues of convalescents from sprue has prompted me to write this preliminary note. In one case culture from the uninflamed tongue was negative, although the patient was desperately ill from one of the intestinal localizations of the disease so familiar to those who know sprue clinically. Only when the intestinal symptoms subsided and the tongue became inflamed was a successful growth obtained. This case has shown repeated and severe desquamatory inflammation of the tongue, so that persistent effort