REDUCTION OF PITUITARY CONTENT OF ACTH BY CORTISONE

Abstract
Dogs were treated with cortisone, 100 mg/day, for 14, 44, and 71 days. Pituitaries were removed and assayed for ACTH content as compared to controls. ACTH content was found to be depressed to 54% of control levels in 14 days, 3% in 44 days and 2% in 71 days.