Syringomas occur with increased frequency in patients with Down's syndrome. It has been previously reported that these lesions are limited to the region around the eyes.1 A patient with Down's syndrome had eruptive syringomas in a plaque-like distribution around the neck. Report of a Case A 17-year-old girl with Down's syndrome was seen in a dermatology clinic for a nonpruritic eruption of her neck of two years' duration. Reportedly, the eruption had arisen in several successive crops of lesions during that time. There was no history of lesions elsewhere on the patient's body, except around the eyes. These lesions were similar to the lesions on the neck and had occurred at approximately the same time. On physical examination, the patient had a typical mongoloid facies. Numerous soft, oblong, fleshy papules, measuring 2 to 5 mm, were distributed in a linear fashion along the skin folds of the anterior aspect of