Zinc-Deficient Embryos: Reduced Thymidine Incorporation
- 21 November 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3908), 1014-1015
- https://doi.org/10.1126/science.166.3908.1014
Abstract
The 12-day-old embryos of rats with a deficiency of zinc showed a reduced uptake of tritiated thymidine when compared with controls, as shown by liquid scintillation and autoradiography. The high incidence of gross congenital malformations resulting from zinc deficiency may thus be caused by DNA impaired DNA synthesis.Keywords
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