A Comparative Study of the Growth of Vesicular Stomatitis Virus in Five Tissue Culture Systems

Abstract

Some properties of the growth of vesicular stomatitis virus in 5 tissue culture systems have been described. Both types of the virus grow most rapidly and with highest yield in chick fibroblast monolayers, and poorest in L cell cultures under the experimental conditions used. Nevertheless, L cells were as susceptible to this virus as chick fibroblasts when used for plaque assays. No differences were found between the 2 isolates studied which were of sufficient magnitude to serve as genetic markers.