Absent Toll-like receptor-9 expression predicts poor prognosis in renal cell carcinoma
Open Access
- 19 September 2011
- journal article
- Published by Springer Nature in Journal of Experimental & Clinical Cancer Research
- Vol. 30 (1), 84-6
- https://doi.org/10.1186/1756-9966-30-84
Abstract
Toll-like receptor 9 (TLR9) is a cellular DNA-receptor whose activation with cognate ligands triggers an immune reaction, with increased production of inflammatory cytokines. The aim of this study was to examine the expression of TLR9 in renal cell carcinoma (RCC), which is generally renowned of its immunogenic nature. We also evaluated the prognostic value of TLR9 in RCC.Keywords
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