In-vitro susceptibility of mycobacteria to ciprofloxacin
- 1 November 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 16 (5), 575-580
- https://doi.org/10.1093/jac/16.5.575
Abstract
Two hundred and seventy-six strains of mycobacteria were tested for susceptibility to ciprofloxacin (Bay 0 9867), a 4-quinolone antimicrobial agent. Most strains of Mycobacterium tuberculosis, Myco. fortuitum, Myco. kansasii, Myco. marinum and Myco. xenopi were sensitive to minimum inhibitory concentrations (MICs) of 0·78–1·56 mg/l, equivalent to resistance ratios of 1 or 2. Most strains of Myco. avium-intracellulare and Myco. chelonei required MICs of 12·5 mg/l or more, giving resistance ratios of 8.Keywords
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