Abstract
The rate of fermentation of a simple sugar by yeast-juice undergoes a temporary acceleration when a soluble phosphate is added. The close chemical analogy which exists between phosphates and arsenates suggested the idea that this similarity might extend to the effect of arsenates on fermentation, and accordingly experiments were made to test the point. It was thus found that arsenates have a great effect on fermentation, but subsequent work has show that it is of a totally different nature from that exerted by phosphates. I. Influence of Arsenate on the Rate of Fermentation. When a solution of sodium arsenate is added to a mixture of glucose, mannose or fructose with yeast-juice, which has attained a steady rate of fermentation, an immediate large increase in the rate of evolution of carbon dioxide is produced. The rate, as a rule, rises for a short period, attains a maximum, and then very gradually diminishes. A typical example is the following.