Improved Acetylating Radioenzymatic Assay of Amikacin, Tobramycin, and Sisomicin in Serum

Abstract
The acetylating radioenzymatic assay of aminoglycosides was modified by using [ 3 H]acetyl coenzyme A as cosubstrate. This modification reduces the cost of the method by at least one-half without sacrificing rapidity or accuracy.