Production of Mucopolysaccharides by Synovial Cells in a Simplified Tissue Culture Medium
- 1 January 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 94 (1), 51-56
- https://doi.org/10.3181/00379727-94-22853
Abstract
Human synovial cells were grown in a semi-synthetic tissue culture medium which excludes embryo extract. Supported by the semi-synthetic medium, the synovial cells produced a mucopolysaccharide believed to be hyaluronic acid on the basis of nondialyzable hexosamine content and susceptibility to hydrolysis by both testicular and bacterial hyaluronidase. Culture morphology, behavior and pattern of mucopolysaccharide production are described.Keywords
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