Growth Inhibition of Free-Living Protozoa by Actidione
- 1 July 1952
- journal article
- research article
- Published by University of Chicago Press in Physiological Zoology
- Vol. 25 (3), 272-276
- https://doi.org/10.1086/physzool.25.3.30152235
Abstract
13 strains of Tetrahymena geleii and Euglena gracilis var. bacillaris (colorless) were studied with respect to actidione tolerance. 1 [mu]./ml. or less, in a medium containing Bacto casitone and Bacto yeast extract at pH 5-6, markedly inhibited growth of all forms. Euglena, and T. geleii GP and Y did poorly with 5 [mu]g./ml. of the antibiotic. Of the remaining ciliates, strain S was the most highly resistant and was capable of growing at the 20 [mu]g. level. By employing a step-up transfer procedure, a variant of strain S was conditioned to a medium containing 50 [mu]g./ml. At pH levels above 6 actidione potency was lost.This publication has 5 references indexed in Scilit:
- Effect of Neomycin on Two Species of Free-Living ProtozoaPhysiological Zoology, 1952
- Chloromycetin and Growth of Certain ProtozoaPhysiological Zoology, 1951
- The Production, Assay, and Antibiotic Activity of Actidione, an Antiobiotic from Streptomyces griseusJournal of Bacteriology, 1948
- Actidione, an Antibiotic from Streptomyces Griseus1Journal of the American Chemical Society, 1948
- ACTIDIONE, AN ANTIBIOTIC FROM STREPTOMYCES GRISEUSJournal of the American Chemical Society, 1947