Prostacyclin infusion in acute cerebral infarction
- 31 October 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 34 (11), 1431
- https://doi.org/10.1212/wnl.34.11.1431
Abstract
We gave prostacyclin infusions to seven patients with acute cerebral infarction. Patients without CT evidence of infarction improved, but those who already had hypodensities on CT did not benefit. Increased platelet activity, measured by plasma beta-thromboglobulin, decreased significantly (p < 0.01) during prostacyclin administration to normal levels, but rose again after the infusion. These results indicate that prostacyclin can be given safely in doses adequate to suppress platelet function. Our findings encouraged us to proceed with a controlled trial of its clinical efficacy.This publication has 7 references indexed in Scilit:
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