Prostaglandins and congeners. 16. Synthesis and bronchodilator activity of dl-11-deoxy-3-thiaprostaglandins
- 1 December 1977
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 20 (12), 1662-1665
- https://doi.org/10.1021/jm00222a024
Abstract
The interesting bronchodilator activity [in guinea pigs] of certain dl-11-deoxy-3-thiaprostaglandins and their preparation by the conjugate addition of appropriately substituted (E)-1-alkenyllithio cuprate reagents to requisite cyclopentenones are described.This publication has 5 references indexed in Scilit:
- Prostaglandins and congeners. 16. Synthesis and bronchodilator activity of dl-11-deoxy-3-thiaprostaglandinsJournal of Medicinal Chemistry, 1977
- Prostaglandins and congeners. 14. Synthesis and bronchodilator activity of dl-16,16-trimethyleneprostaglandinsJournal of Medicinal Chemistry, 1977
- Metabolism of 16,16-dimethyl-Prostaglandin F2α in the cynomolgus monkey and the human femaleBiochemical Medicine, 1976
- VENTILATORY MECHANICS IN DOG - ITS APPLICATION TO QUANTITATIVE STUDY OF BRONCHOMOTOR ACTIVE DRUGS1967
- Ventilation standards for small mammalsJournal of Applied Physiology, 1964