Published research on the osseous development of the bones of the hand and wrist in mongolism indicates that these children do not differ materially from normal children in this aspect of development. For example, Benda1reported that the first appearance of the centers of ossification was premature, with normal development of the carpals between 2 and 14 years of age. Werner 12 noted that of eight cases studied over a period of four years, the ossification in some was normal, whereas in others the appearance of the bony nuclei was delayed. Hefke4in a roentgenographic study of the hands of 72 mongols found that 57 showed normal osseous development, 10 showed slightly advanced ossification, and 5 were slightly delayed. According to the latter investigator the deviations were not marked in any patient. Hefke's findings were in general supported by Oster7who reported that of 87 mongoloid cases