A single dose study of trazodone with an assessment of its effect on mood and arousal.
- 1 February 1975
- journal article
- clinical trial
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 2 (1), 19-24
- https://doi.org/10.1111/j.1365-2125.1975.tb00466.x
Abstract
1 A pharmacokinetic study of a single oral dose of a new antidepressant (trazodone) is described, linked to an attempt to measure changes in mood and arousal induced by the drug in normal subjects. 2 The drug had a measurable effect on arousal, but not on mood. It caused bradycardia (compared with placebo) and this persisted through the following night's sleep. This effect has not been completely explained. 3 The technique of mood and arousal measurement employed in this study seems potentially useful.Keywords
This publication has 4 references indexed in Scilit:
- Clinical experience with a new psychotropic drug, trazodone: a review of literature.1973
- Measurement of feelings using visual analogue scales.1969
- A Growing Edge of Measurement of Feelings [Abridged]Proceedings of the Royal Society of Medicine, 1969
- A Short Clinical Diagnostic Self-rating Scale for Psychoneurotic PatientsThe British Journal of Psychiatry, 1966