Biochemical Markers in Lymphoid Malignancy

Abstract

HISTORICALLY, the classification of lymphoid cancer has been based on morphologic assessment with the light microscope. The observation that lymphoid cells can be categorized according to immunologic cell-surface markers has provided an additional, more refined approach to the classification of these diseases. Recently, a number of enzyme abnormalities have been described in malignant lymphoid cells. A survey of this work suggests that characterization of these enzymes may provide a valuable tool for further definition of subsets of leukemia and lymphoma. In addition to conventional clinical and laboratory data, a biochemical profile may be useful in the diagnosis and treatment of . . .