The phylogenetic distribution of bacterial ribonucleases
Open Access
- 15 December 2002
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 30 (24), 5339-5346
- https://doi.org/10.1093/nar/gkf691
Abstract
Ribonucleases play key, often essential, roles in cellular metabolism. Nineteen ribonuclease activities, from 22 different proteins, have so far been described in bacteria, the majority of them from either Escherichia coli or Bacillus subtilis. Here we examine the phylogenetic distribution of all of these ribonucleases in 50 eubacterial and archaeal species whose genomes have been completely sequenced, with particular emphasis on the endoribonucleases. Although some enzymes are very highly conserved throughout evolution, there appears to be no truly universal ribonuclease. While some organisms, like E.coli, have a large selection of ribonucleases, many with overlapping functions, others seem to have relatively few or have many that remain to be discovered.Keywords
This publication has 63 references indexed in Scilit:
- Escherichia coli RNase M is a multiply altered form of RNase I.2001
- Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegansGenes & Development, 2001
- Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operonMolecular Microbiology, 2001
- The Plant tRNA 3‘ Processing Enzyme Has a Broad Substrate SpectrumBiochemistry, 2001
- Exoribonuclease superfamilies: structural analysis and phylogenetic distributionNucleic Acids Research, 2001
- Identification of the gene encoding the 5S ribosomal RNA maturase in Bacillus subtilis: mature 5S rRNA is dispensable for ribosome function.RNA, 2001
- Role for a bidentate ribonuclease in the initiation step of RNA interferenceNature, 2001
- A Natural Classification of RibonucleasesMethods in Enzymology, 2001
- Endoribonuclease RNase III is essential in Bacillus subtilisMolecular Microbiology, 2000
- RNase G (CafA protein) and RNase E are both required for the 5′ maturation of 16S ribosomal RNAThe EMBO Journal, 1999