Mechanism of Production of Papilledema in the Guillain‐Barré Syndrome

Abstract

It does not appear that increased cerebrospinal fluid pressure and papilledema found in the Guillain-Barre syndrome are a consequence of blockage of fluid absorption by high protein levels of the cerebrospinal fluid. It is more likely due to intrinsic cerebral edema similar to that found in cases of pseudo-tumor cerebri. It is possible that the factors responsible for the prominent nerve root edema in the Guillain-Barre syndrome may also result in cerebral edema in certain cases.