Sialic Acid: Effect of Removal on Calcium Exchangeability of Cultured Heart Cells
- 10 September 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 193 (4257), 1013-1015
- https://doi.org/10.1126/science.948758
Abstract
Specific removal of sialic acid from cultured heart cells with purified neuraminidase increases cellular calcium exchangeability. Potassium exchange is unaffected or slightly decreased. Sialic acid removal also permits lanthanum, normally restricted to the cellular surface, to enter the cells and displace more than 80 percent of cellular calcium. The results indicate a specific role of cellular surface components in the control of calcium exchangeability in the heart.This publication has 14 references indexed in Scilit:
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