Virus Neutralizing Antibodies in Pooled Human Serum
- 30 November 1953
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 71 (6), 402-409
- https://doi.org/10.4049/jimmunol.71.6.402
Abstract
The titer of neutralizing antibodies to Coxsackie viruses in pooled human serum and human gamma globulin has been estimated in samples covering a period of twelve years. The construction of antibody titer curves for each infective agent demonstrated marked differences in the behaviour of some of the Coxsackie viruses. It was shown that group A and group B Coxsackie virus antibodies were widespread throughout the Western Pacific Area and present in all sera examined. Antibody to the group of Coxsackie viruses associated with an outbreak of encephalitis in Sydney was confined to the Sydney Metropolitan Area and to some of the Highland natives of New Guinea. It is thought that the nature of the antibody titer curves reflects to some extent the degree of immunity of the adult population of a large city to the infective agent under consideration. The estimation of the herpetic antibody content of pooled human serum was used for comparison.Keywords
This publication has 3 references indexed in Scilit:
- A HITHERTO UNDESCRIBED GROUP OF COXSACKIK VIRUSES ASSOCIATED WITH AN OUTBREAK OF ENCEPHALITISImmunology & Cell Biology, 1953
- STUDIES ON AUSTRALIAN STRAINS OF COXSACKIE VIRUS (GROUPS A AND B)Immunology & Cell Biology, 1953
- ANTIBODIES TO COXSACKIE VIRUSES IN POOLED HUMAN SERUMImmunology & Cell Biology, 1953