Single Day or Single Dose Treatment of Urinary Tract Infection with Co-trimoxazole
- 1 December 1980
- journal article
- research article
- Published by Wiley in Australian and New Zealand Journal of Medicine
- Vol. 10 (6), 604-607
- https://doi.org/10.1111/j.1445-5994.1980.tb04239.x
Abstract
Forty-eight women with urinary tract infection due to co-trimoxazole sensitive organisms [bacteria] were randomly allocated to receive 2 tablets (0.96 g) of co-trimoxazole twice a day for 1 day, 4 tablets (1.92 g) of co-trimoxazole as a single dose or 2 tablets of co-trimoxazole twice a day for 7 days. The infection cure rate was comparable in each group being 82, 87 and 81%, respectively. The patients who received the single dose had a high incidence of minor side effects. One-day treatment appears to be the treatment mode of choice. Failure to respond to single dose or single day treatment may indicate those patients requiring investigation of their urinary tract.This publication has 11 references indexed in Scilit:
- EFFECT OF CO-TRIMOXAZOLE ON NORMAL CREATININE CLEARANCEThe Lancet, 1978
- Treatment of Urinary-Tract Infection with a Single Dose of AmoxycillinNephron, 1977
- Localization of Urinary-Tract Infections by Detection of Antibody-Coated Bacteria in Urine SedimentNew England Journal of Medicine, 1974
- Antibody-Coated Bacteria in the Urine and the Site of Urinary-Tract InfectionNew England Journal of Medicine, 1974
- DETERIORATION IN RENAL FUNCTION IN ASSOCIATION WITH CO-TRIMOXAZOLE THERAPYThe Lancet, 1973
- Single-dose Therapy with Streptomycin and Sulfametopyrazine for Bacteriuria during PregnancyBMJ, 1970
- Single-dose treatment of acute urinary tract infection: a controlled trial.BMJ, 1967