Ascorbic acid and phosphatase activity

Abstract

Hydrolysis of the commonly used phosphoric esters by serum phosphatase was not appreciably affected by ascorbic acid. Ascorbic acid did not activate phosphatase. No support was found for the contention of Thannhauser et al. [1937] that the high serum phosphatase values encountered in certain diseases was due to the presence of an activator in the serum rather than to an accumulation of the enzyme itself.