UREA INHIBITION OF HUMAN PSEUDOCHOLINESTERASEA
Open Access
- 1 January 1971
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 43 (1), 51-53
- https://doi.org/10.1093/bja/43.1.51
Abstract
A method for differentiating between the usual and atypical pseudocholinesterases in serum using urea is described. The method can be used for detecting suxamethonium-sensitive individuals. The results from studies of urea inhibition indicate that the atypical pseudocholinesterase is less stable in its tertiary protein structure than is the usual enzyme.Keywords
This publication has 4 references indexed in Scilit:
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- The Solubility of Amino Acids and Related Compounds in Aqueous Urea SolutionsJournal of Biological Chemistry, 1963
- HARRIS AND WHITTAKERS PSEUDOCHOLINESTERASE VARIANT WITH INCREASED RESISTANCE TO FLUORIDE - A STUDY OF 4 FAMILIES AND IDENTIFICATION OF HOMOZYGOTE1963
- Differential Inhibition of Human Serum Cholinesterase with Fluoride: Recognition of Two New PhenotypesNature, 1961