Viral Shedding and Transmission Between Hosts Determined by Reovirus L2 Gene
- 27 June 1986
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 232 (4758), 1635-1638
- https://doi.org/10.1126/science.3012780
Abstract
Two reovirus isolates (type 1 Lang and type 3 Dearing) differ in their transmissibility between littermates of newborn mice. They also differ in the amounts of virus excreted by the gastrointestinal tract. With the use of reassortant viruses, these properties were mapped to the L2 gene. Thus environmental spread of reovirus is a genetic property.This publication has 14 references indexed in Scilit:
- Pathogenesis of Viral InfectionsNew England Journal of Medicine, 1985
- Genetic Studies on the Mechanism of Chemical and Physical Inactivation of ReovirusJournal of General Virology, 1982
- Intestinal M Cells: A Pathway for Entry of Reovirus into the HostScience, 1981
- The interaction of a series of hybridoma IgGs with reovirus particles Demonstration that the core protein λ2 is exposed on the particle surfaceVirology, 1981
- Molecular basis of reovirus virulence. Role of the M2 gene.The Journal of Experimental Medicine, 1980
- A genetic map of reovirus I. Correlation of genome RNAs between serotypes 1, 2, and 3Virology, 1978
- Use of an aberrant polypeptide as a marker in three-factor crosses: Further evidence for independent reassortment as the mechanism of recombination between temperature-sensitive mutants of reovirus type 3Virology, 1976
- Studies on the structure of reovirus cores: Selective removal of polypeptide λ2Virology, 1976
- Temperature-sensitive mutants of reovirus type 3: Defects in viral maturation as studied by immunofluorescence and electron microscopyVirology, 1971
- EXPERIMENTAL TRANSMISSION OF INFLUENZA VIRUS INFECTION IN MICEThe Journal of Experimental Medicine, 1967