Uterine and oviducal protein secretion during early pregnancy in the mouse
- 1 September 1987
- journal article
- research article
- Published by Bioscientifica in Reproduction
- Vol. 81 (1), 287-294
- https://doi.org/10.1530/jrf.0.0810287
Abstract
Changes in the protein composition of the embryo''s environment during early development were studied by analysis of protein synthesized and secreted by oviducal and uterine explants on Days 1-6 of pregnancy. Although secretions from ampullar and isthmic oviduct and uterus contained many proteins in common, each area also produced its own characteristic proteins. In the uterus, changes in the secretion pattern were found during the peri-implantation period, including both increases and decreases in particular proteins which appear to be dependent on the presence of embryos. Embryo-induced effects on uterine secretion began between 09:00 h of Day 4 and 09:00 h of Day 5. Oviducal secretions exhibited many of the embryo-dependent proteins found in the uterus, but the expression of these proteins did not appear to be influenced by the presence of embryos on Day 1 or Day 3. The characteristic pattern of secreted protein expression by each portion of the reproductive tract may reflect the specialization of each area for certain developmental events.Keywords
This publication has 17 references indexed in Scilit:
- Radiolabelled uterine proteins during early pregnancy and pseudopregnancy in mice after unilateral ovariectomy and superovulationReproduction, 1980
- Early pregnancy factor: Tissues involved in its production in the mouseJournal of Reproductive Immunology, 1980
- Estrogen-dependent and progesterone-arrested synthesis and secretion of sulfated glycoproteins in luminal epithelia of rat uteriBiochimica et Biophysica Acta (BBA) - General Subjects, 1979
- Analysis of mouse uterine proteins at pro-oestrus, during early pregnancy and after administration of exogenous steroidsReproduction, 1979
- Proteins of Follicular, Bursal and Ampullar Fluids of RatsBiology of Reproduction, 1977
- Radiolabelled rat uterine luminal proteins and their regulation by oestradiol and progesteroneReproduction, 1977
- Qualitative and quantitative examination of the proteins of rat uterine luminal fluid during pro-oestrus and pregnancy and comparison with those of serumReproduction, 1977
- Changes in the protein content of mouse uterine flushings during normal pregnancy and delayed implantation, and after ovariectomy and oestradiol administrationReproduction, 1977
- LOSS OF THE ZONA PELLUCIDA IN MICE, AND THE EFFECT OF TUBAL LIGATION AND OVARIECTOMYReproduction, 1967
- INDUCTION OF SUPEROVULATION AND PREGNANCY IN MATURE MICE BY GONADOTROPHINSJournal of Endocrinology, 1957