Withania Somnifera(Ashwagandha), a Rejuvenating Herbal Drug Which Enhances Survival During Stress (an Adaptogen)
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in International Journal of Crude Drug Research
- Vol. 20 (1), 29-35
- https://doi.org/10.3109/13880208209083282
Abstract
Withania somnifera, herbal rejuvenative tonic widely used by Ayurvedic physicians in India, was tested for its adaptogenic properties. Pretreatment with this drug increased the swimming endurance in mice. It prevented gastric ulcers induced chemically or by stress in rats. Milk-induced leucocytosis was also prevented in mice. The drug prevented increase in adrenal weight and decrease in ascorbic acid and Cortisol content of adrenals during stress. It appears to induce a state of non-specifically increased resistance (SNIR) during stress.Keywords
This publication has 8 references indexed in Scilit:
- An Experimental Evaluation of Anti-Stress Effects of ‘Geriforte’ (an Ayurvedic Drug)Quarterly Journal of Crude Drug Research, 1978
- An Experimental Evaluation of Protective Effects of Some Indigenous Drugs on Carbon Tetrachloride-Induced Hepatotoxicity in Mice and RatsQuarterly Journal of Crude Drug Research, 1978
- Effect of a single dose of phentolamine and MJ 1999 on aspirin-induced gastric ulceration in ratsJournal of Pharmacy and Pharmacology, 1969
- An investigation of antihistaminic activity and gastric ulcerationEuropean Journal of Pharmacology, 1969
- New Substances of Plant Origin which Increase Nonspecific ResistanceAnnual Review of Pharmacology, 1969
- Synergism Between Gold and Restraint for Rapid Production of Stress Ulcers in Rats.Experimental Biology and Medicine, 1967
- THE DETERMINATION OF ASCORBIC ACID IN WHOLE BLOOD AND URINE THROUGH THE 2,4-DINITROPHENYLHYDRAZINE DERIVATIVE OF DEHYDROASCORBIC ACIDJournal of Biological Chemistry, 1943
- EXPERIMENTAL EVIDENCE SUPPORTING THE CONCEPTION OF "ADAPTATION ENERGY"American Journal of Physiology-Legacy Content, 1938