Localization of phosphorus metabolites and sodium ions in the rat kidney

Abstract

Relative amounts of phosphorus-containing metabolites and sodium ions present in different regions of the in vivo rat kidney were obtained using a surface-coil probe and recently developed NMR rotating-frame methods. During altered physiologic states, changes in distribution of metabolites and sodium ions within the kidney were identified in one-dimensional metabolite maps. This technique may have important applications to disorders commonly found in clinical medicine. © 1986 Academic Press, Inc.