The role of Th1/Th2 polarization in mucosal immunity
Top Cited Papers
- 1 June 2002
- journal article
- review article
- Published by Springer Nature in Nature Medicine
- Vol. 8 (6), 567-573
- https://doi.org/10.1038/nm0602-567
Abstract
Mucosal immunity relies on the delicate balance between antigen responsiveness and tolerance. The polarization of T helper cells plays a key role in maintaining or disrupting this equilibrium.Keywords
This publication has 99 references indexed in Scilit:
- Crohn's diseaseThe Lancet, 2002
- AsthmaNew England Journal of Medicine, 2001
- Crucial Role of the Interleukin 1 Receptor Family Member T1/St2 in T Helper Cell Type 2–Mediated Lung Mucosal Immune ResponsesThe Journal of Experimental Medicine, 1999
- Lineage-specific Requirement for Signal Transducer and Activator of Transcription (Stat)4 in Interferon γ Production from CD4+ Versus CD8+ T CellsThe Journal of Experimental Medicine, 1999
- IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESSAnnual Review of Immunology, 1999
- The Th1/Th2 paradigmImmunology Today, 1997
- TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and FunctionAnnual Review of Immunology, 1997
- Reciprocal IFN-γ and TGF-β responses regulate the occurrence of mucosal inflammationImmunology Today, 1997
- The expanding universe of T-cell subsets: Th1, Th2 and moreImmunology Today, 1996
- Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral DiseaseCell, 1996