N-Benzylhydroxylamine Addition to β-Aryl Enoates. Enantioselective Synthesis of β-Aryl-β-amino Acid Precursors
- 29 September 2000
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 2 (21), 3393-3396
- https://doi.org/10.1021/ol006500e
Abstract
Chiral Lewis acid catalyzed N-benzylhydroxylamine addition to pyrrolidinone-derived enoates afforded beta-aryl-beta-amino acid derivatives in high enantiomeric purity with moderate to very good chemical efficiency.Keywords
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