Susceptibility of hepatitis B virus to disinfectants or heat

Abstract

Direct chimpanzee inoculation was used as an assay to test the abilities of the following chemical or physical treatments to inactivate hepatitis B virus in human plasma: 1% aqueous glutaraldehyde at 24.degree. C for 5 min, 0.1% aqueous glutaraldehyde at 24.degree. C for 5 min, 80% ethyl alcohol at 11.degree. C for 2 min, and heat at 98.degree. C for 2 min. All treatments were effective, indicating that the resistance level of the hepatitis B virus is not extreme.