The effect of colchicine on the acid-soluble ribonucleotides of normal and regenerating rat liver

Abstract
The concentrations of the acid-soluble ribonucleotides in the livers of normal and partially hepatectomized rats and of normal and partially hepatectomized rats treated with either colchicine or Myleran (busulfan) were measured. Although the treatment with drugs had little effect on the majority of the nucleotides colchicine caused the concentrations of NAD and AMP to increase and those of ATP, GTP and UTP to decrease.