Plasma Pseudorenin in Rats after Alteration in the Renin-Angiotensin System

Abstract
Plasma levels of renin and pseudorenin were measured at various times in control rats, and after bilateral nephrec-tomy, treatment with propranolol, or the converting enzyme inhibitor (CEI) SQ 20881. After nephrectomy or propranolol, renin levels decreased but pseudorenin levels increased. Following treatment with CEI, renin levels rose in a nonoperated animal and remained very low in a nephrecto-mized animal. Pseudorenin levels did not change appreciably after CEI in either animal.

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