Effect of Neonatal Thymectomy on Ovarian Development and Plasma LH, FSH, GH and PRL in the Mouse1
Open Access
- 1 March 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 22 (2), 343-350
- https://doi.org/10.1093/biolreprod/22.2.343
Abstract
Neonatal thymectomy at 3 days of age (Tx-3) in (C57BL/6Cr × A/JCr)F1 female mice resulted in ovarian changes characterized by lymphocyte infiltration of the follicles, a decline in oocyte numbers and hypertrophy of the interstitial cell elements. These changes were associated with reduced levels of circulating LH, FSH and GH. Although there is a clear interrelationship of the thymus with the pituitary and ovary, it is not yet clear whether the relationship is only immunological or if there is an additional hormonal relationship.This publication has 8 references indexed in Scilit:
- Initiation of Follicular Growth in the Infant Mouse Ovary by Exogenous GonadotrophinBiology of Reproduction, 1977
- Ovarian Follicular Development in the Rat: Hormone Receptor Regulation by Estradiol, Follicle Stimulating Hormone and Luteinizing Hormone1Endocrinology, 1976
- Ovarian development in athymic nude mice V. The effects of PMSG upon the numbers and growth of follicles in the early juvenile ovaryMechanisms of Ageing and Development, 1976
- Effect of neonatal thymectomy on follicle numbers in the post-natal mouse ovaryMechanisms of Ageing and Development, 1976
- Correlation of serum gonadotropins, ovarian and uterine histology in immature and prepubertal ratsThe Anatomical Record, 1974
- Histology of the anterior hypophysis, thyroid and gonads of two types of dwarf miceThe Anatomical Record, 1964
- THE EFFECT OF HYPOPHYSECTOMY ON AGE CHANGES IN THE OVARIES OF MICEJournal of Endocrinology, 1961
- EVIDENCE THAT THE HYPOTHALAMUS IS RESPONSIBLE FOR ANDROGEN-INDUCED STERILITY IN THE FEMALE RAT1Endocrinology, 1961