Phenotype–Genotype Profiles in Crohnʼs Disease Predicted by Genetic Markers in Autophagy-Related Genes (GOIA Study II)
Open Access
- 1 February 2013
- journal article
- research article
- Published by Oxford University Press (OUP) in Inflammatory Bowel Diseases
- Vol. 19 (2), 230-239
- https://doi.org/10.1002/ibd.23007
Abstract
Background. About 70 loci are associated with susceptibility to Crohn's disease (CD), particularly in pathways of innate immunity, autophagy, and pathogen recogKeywords
This publication has 41 references indexed in Scilit:
- Genetics of inflammatory bowel disease in Asia: Systematic review and meta-analysisInflammatory Bowel Diseases, 2012
- Metagenomics and Personalized MedicineCell, 2011
- Recent Insights Into the Genetics of Inflammatory Bowel DiseaseGastroenterology, 2011
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's diseaseNature Genetics, 2008
- Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsNature, 2007
- Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibilityNature Genetics, 2007
- A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1Nature Genetics, 2006
- Differential Effects of NOD2 Variants on Crohn's Disease Risk and Phenotype in Diverse Populations: A MetaanalysisAmerican Journal of Gastroenterology, 2004
- Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseNature, 2001
- A frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseNature, 2001