The frequency and distribution of sister chromatid exchanges in human chromosomes
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 38 (3), 271-278
- https://doi.org/10.1007/bf00402152
Abstract
The distribution of sister chromatid exchanges (SCEs) both between and within chromosomes was studied in cultured human lymphocytes using the BRDU-Giemsa technique. In general, the distribution of SCEs between chromosomes was a function of chromosome length. However, chromosomes of the B group had more exchanges than expected on this basis, while the E, F, and G groups had less than expected. Analysis of cells showing both G-banding and sister chromatid differential staining indicates that the distribution of exchanges within the chromosomes is non-random and possible reasons for the observed distribution pattern are discussed.This publication has 32 references indexed in Scilit:
- Preferential location of X-ray induced chromosome breakage in the R-bands of human chromosomesHereditas, 2009
- Distribution of mitomycin C induced breaks on human chromosomesHereditas, 2009
- Identification withGandRBanding of the Position of Breakage Points Induced in Human Chromosomes byin VitroX-irradiationInternational Journal of Radiation Biology, 1976
- Sister chromatid exchange in human chromosomes from normal individuals and patients with ataxia telangiectasiaCytogenetic and Genome Research, 1975
- Spontaneous sister chromatid exchanges detected by a BUdR-labelling methodNature, 1974
- Sister chromatid exchanges induced by light flashes to 5-bromodeoxyuridine- and 5-iododeoxyuridine substituted Chinese hamster chromosomesExperimental Cell Research, 1974
- Localization of Sister Chromatid Exchanges in Human ChromosomesScience, 1974
- Nonrandom distribution of chromosome breaks in Fanconi’s anemiaCytogenetic and Genome Research, 1973
- Heterochromatin of the Indian muntjac: Replication, condensation, DNA ultracentrifugation, fluorescent and heterochromatin stainingExperimental Cell Research, 1971
- Die wirkung von thioguanin, hydroxylamin unde 5-bromdesoxyuridin auf menschliche chromosomen in vitroMutation Research, 1967