In the United States dangerous poisoning by the bite of the rattlesnake is comparatively infrequent, but deaths do occur in some sections of the country where these snakes are particularly abundant and of large size. Bites in children are especially dangerous, probably because of the low body weight in proportion to the amount of venom injected. One of us1has shown that it is possible to remove venom from the tissues by mechanical means, and the experiments here reported are in the nature of a confirmatory report. The venom used throughout these experiments was an unrefined, air dried product which was dissolved in a solution composed of equal parts of glycerin and 0.85 per cent sodium chloride solution, in the proportion of 0.050 Gm. of dried venom to 1 cc. of solution. This stock solution of venom was kept at 10 C. The dogs used were of varying sizes