Introduction MUCH HAS BEEN written about various sorts of treatment for oral cavity carcinoma. The present report is presented in an effort to describe in some detail our own experience with radical surgery for this disease and to compare it with similar reports from the literature. Included in the series are cancer of the tongue, floor of the mouth, tonsil, gingiva, buccal mucosa, and pharynx, and excluded are cancer of the lip, the larynx, and the hard and soft palate. All were squamous-cell carcinomas usually well or moderately well differentiated. In some respects the lesions being considered here are quite similar: they occurred in males, they were all squamous-cell carcinomas, there was a moderately high incidence of neck lymph node metastasis and low clinical incidence of distant metastasis, and patients who died usually had uncontrolled local disease with concomitant inanition and pneumonia. Otherwise, however, some oral lesions, depending upon their