Proliferative activity of myocardial capillary wall cells in dipyridamole-treated rats
- 1 November 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 12 (11), 692-695
- https://doi.org/10.1093/cvr/12.11.692
Abstract
The hearts of rats treated with dipyridamole were studied by light microscope autoradiography and measurement of tissue radioactivity after intravenous injection of 3H-thymidine. Total tissue radioactivity was significantly increased in the hearts of the dipyridamole-treated animals. Only capillary wall cells were labelled in the autoradiograms. The observations indicate a proliferation of capillary wall cells, suggesting a neoformation of myocardial capillaries during dipyridamole treatment.Keywords
This publication has 5 references indexed in Scilit:
- THE MYOCARDIAL CAPILLARY VASCULATURE IN EXERCISING ANIMALS WITH INCREASED CARDIAC PRESSURE LOADActa Pathologica Microbiologica Scandinavica Section A Pathology, 2009
- Influence of long-term treatment with dipyridamole on the aorta-stenosed rabbit heart: morphometric and functional investigationsCardiovascular Research, 1976
- Cell proliferation in developing coronary collaterals and the influence of lidoflazine on this processJournal of Molecular and Cellular Cardiology, 1976
- VARIATION OF MECHANICAL AND BIOCHEMICAL PARAMETERS OF PRESSURE-LOADED RABBIT HEARTS FOLLOWING CHRONIC ADMINISTRATION OF DIPYRIDAMOLE1975
- A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acidBiochemical Journal, 1956