Antidepressants in Black and White Inpatients
- 1 May 1975
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 32 (5), 643-649
- https://doi.org/10.1001/archpsyc.1975.01760230109008
Abstract
Differential effects of chlorpromazine, imipramine hydrochloride, and a placebo were examined in 159 black and 555 white depressed patients in a multihospital collaborative study. In making these comparisons, the effects of age and social class were controlled. The major study findings were the differential effects of the active drugs for the black men and women. Chlorpromazine was the most efficacious treatment for black women, whereas imipramine was most efficacious for black men. These differences occurred on global ratings of improvement as well as on specific symptoms such as depression, anxiety, guilt-worthlessness, sleep disturbances, and social participation. Black patients also evidenced a higher improvement rate at one week, irrespective of treatment, than did the white patients.Keywords
This publication has 12 references indexed in Scilit:
- Multiple covariance analysis by the general least squares regression methodBehavioral Science, 1972
- Super factors of psychopathology in hospitalized depressed patientsJournal of Psychiatric Research, 1971
- MMPI study of Negro mental hygiene clinic patients.Journal of Abnormal Psychology, 1968
- Minimal effects of severe depression on cognitive functioning.The Journal of Abnormal and Social Psychology, 1964
- THE EFFECT OF CHLORPROMAZINE ON THE VARIABILITY OF MOTOR TASK PERFORMANCE IN SCHIZOPHRENICSJournal of Nervous & Mental Disease, 1960
- An inventory for assessing different kinds of hostility.Journal of Consulting Psychology, 1957
- COMFORT, EFFECTIVENESS, AND SELF-AWARENESS AS CRITERIA OF IMPROVEMENT IN PSYCHOTHERAPYAmerican Journal of Psychiatry, 1954
- A comparative study of psychoses among negroes and whites in the New York State prisonsPsychiatric Quarterly, 1939
- Migration and mental disease among Negroes in New York stateAmerican Journal of Physical Anthropology, 1936
- Race and mental disease in New York StatePsychiatric Quarterly, 1935