Evolution of ageing
- 1 November 1977
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 270 (5635), 301-304
- https://doi.org/10.1038/270301a0
Abstract
An evolutionary view of ageing suggests that mortality may be due to an energy-saving strategy of reduced error regulation in somatic cells. This supports Orgel's ‘error catastrophe’ hypothesis and offers a new basis for the study of normal and abnormal ageing syndromes and of apparently immortal transformed cell lines.Keywords
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