Irreversible Nature of the Stacked β-Pleated Sheets of a Model Polypeptide
- 1 September 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 60 (9), 3438-3440
- https://doi.org/10.1246/bcsj.60.3438
Abstract
A mode of association of β-sheets, most probably the stacking of the pleated sheets, has been studied by circular dichroism and light scattering on the 5×10−2 mol dm−3 NaCl solutions of poly(S-carboxymethyl-L-cysteine). It was found that the association is highly irreversible with respect to concentration change at constant pH. Relevance of the study of synthetic polypeptides is discussed in relation to the association mode found in proteins.Keywords
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